Present plants study was carried out in Sarkaghat Tehsile of Mandi District of Himachal Pradesh of North- West Himalayas for their medicinal uses by the local people of study area from ancient time. The human relationship with the plants is too old as old the existence of life. Plants are most important source of medicine from the ancient period. The aim of this study is to document the traditional knowledge on the utilization of plants by the locals. There is no previous work done any workers and all the information mentioned the paper is derived from the people of the area. In present paper 60 medicinal plants of belonging to 59 genera of 44 families. Plant parts leaves, stem, root, rhizome, fruit and flowers are used by the local inhabitant for the treatment of various diseases.