Article Abstract
International Journal of Trends in Emerging Research and Development, 2025;3(1):127-134
Role of phytochemicals in the pharmacological management of neurodegenerative disorders
Author : Reshu Jain and Dr. Utkarsh Mishra
Abstract
Neurodegenerative diseases are a broad category of pathological illnesses characterized by the gradual deterioration of neuronal cells and the connections between the nervous system. These disorders mainly affect neuronal dysfunction and may lead to issues with movement, thinking, feeling, and strength. Molecular studies have shown that aberrant protein aggregation, neuroinflammation, mitochondrial malfunction, excessive production of reactive oxygen and nitrogen species, and other stress-related metabolic changes may cause neuronal cell death. Standard treatments for neurodegenerative diseases may only alleviate symptoms and slow the disease's course; none of these diseases are currently treatable. Because they are progressive and currently have no cure, neurodegenerative disorders like Alzheimer's, Parkinson's, and Huntington's present enormous obstacles. More and more research is focusing on phytochemicals-bioactive substances sourced from plants-and their potential neuroprotective benefits, such as antioxidant, anti-inflammatory, and anti-apoptotic capabilities.
Keywords
Neurodegenerative, Phytochemicals, Neuroprotective, Diseases, Symptoms