It is the purpose of this randomised controlled trial to investigate the gender variations that exist in the responses to Multi-Component Yoga (MCY) therapy for the treatment of insomnia and other related psychological disorders, such as anxiety and depression. An MCY intervention that lasted for eight weeks was carried out on a total of 120 participants, with males and females sharing an equal number of participants. Validated scales such as the Pittsburgh Sleep Quality Index (PSQI), the Insomnia Severity Index (ISI), the State-Trait Anxiety Inventory (STAI), and the Beck Depression Inventory (BDI) were utilised in order to assess the quality of sleep, the severity of insomnia, anxiety, and depressive symptoms. The findings showed that both males and females experienced significant increases in the quality of their sleep as well as reductions in the intensity of their occurrence of insomnia. There were no discernible differences between the two groups. Nevertheless, as compared to males, girls showed much higher reductions in the symptoms of anxiety and depression throughout the study. Based on these findings, it appears that MCY therapy is similarly beneficial for controlling insomnia in both males and females, although it may offer additional psychological benefits to females.