abstract

Post-Traumatic Stress Disorder (PTSD) is a complex mental health condition that often requires multifaceted treatment approaches. While pharmacological interventions such as selective serotonin reuptake inhibitors (SSRIs) remain a first-line treatment, many patients experience only partial relief or relapse upon discontinuation. This study investigates the synergistic effects of combining Mindfulness-Based Cognitive Therapy (MBCT) with standard pharmacotherapy in individuals diagnosed with PTSD. A randomized controlled trial was conducted with 120 participants divided into three groups: pharmacotherapy only, MBCT only, and a combined treatment group. Quantitative data were collected over 12 weeks using the Clinician-Administered PTSD Scale (CAPS-5), Beck Depression Inventory-II (BDI-II), and Five Facet Mindfulness Questionnaire (FFMQ). Results indicated that the combined treatment group exhibited significantly greater symptom reduction, improved emotional regulation, and increased mindfulness compared to either intervention alone. The findings support an integrative approach, suggesting that MBCT may enhance the therapeutic efficacy of pharmacological treatment by addressing cognitive and emotional dimensions often resistant to medication alone.