abstract

The ever-increasing danger posed by antimicrobial resistance has made it necessary to investigate alternate microbiological sources in order to find new drugs. This research analyses the possible antibacterial properties of endophytic fungi that have been isolated from the medicinal plant Mirabilis jalapa. The microorganisms that are the focus of this investigation are both human and phytopathogenic. We discovered numerous strains that exhibited strong inhibitory activity by isolating them, characterising them morphologically and molecularly, and conducting agar diffusion studies. The results of additional analysis using chromatographic methods indicated the presence of secondary metabolites that possessed antimicrobial properties. In light of the fact that antibiotic resistance is a global problem, these findings suggest that endophytic fungi could be a valuable source of bioresources for the development of novel antibiotics.