abstract

The antiviral medications in pharmaceutical dose forms were identified by the anticancer drugs were calculated using RP-HPLC, while their separated forms were evaluated using UPLC. Since the placebo peak did not interact with the medication peaks, all of the approaches were determined to be selective. Since the percentages of recovery and RSD were within the specified ranges, it was determined that the procedures were accurate and exact as well. At concentrations within their respective limits, all of the approaches exhibited Beer's law compliance (r=0.999). The approach was deemed robust since the % RSD remained within the specified parameters. We tested the method's resilience by changing the mobile phase's organic phase composition, flow rate, and column oven temperature. We discovered that it worked well. The pharmaceuticals remained stable throughout a wide range of circumstances, including from heat to acidic to basic to oxidative to neutral to photolytic to photolytic of all approaches. According to the results, both the peak purity angle and the net deterioration were below the peak purity criterion.