Abstract
International Journal of Trends in Emerging Research and Development, 2024;2(4):23-26
Syzygium aromaticum Methanol Extract [SAME] phytochemical analysis and its role on pathogenic organisms
Author : Lakshman R, Harish S, Sangita Roy, Ashwini S, Deepa G, Mahamad PH and Sharath Kumar MN
Abstract
The aim of this work is to explore the possible medical applications of Syzygium aromaticum Methanol Extract [SAME]. SAME has an abundance of macro and micronutrients, including phytosterol, phenolic compounds, saponins, flavonoids, and more, based on the results of the initial screening assay. GC-MS and HPLC analyses, which yielded chromatograms with 11 and 6 peaks, respectively, demonstrating the presence of various phytochemicals, also confirmed their presence. Furthermore, minerals like zinc, manganese, iron, boron, and aluminum are present in the SAME extract. In addition to the tests mentioned above, we are fortunate to have found that SAME's non-toxic property keeps it from cleaving packed red blood cells in in vitro tests. SAME surprisingly possesses antibacterial qualities against gram positive bacteria (S. aureus) and gram negative bacteria (E. coli). Amoxicillin used as a positive control. The minimum inhibitory concentration for both the organisms is 1.4 and 0.8 value respectively.
Keywords
Syzygium aromaticum Methanol Extract [SAME], GC-MS, RP-HPLC, Anti-bacterial and Non-toxic property